IMHO the best versions are the ones that do not remove region code setting, but do not remember the changes permanently. So each time you turn on your computer, you get a fresh drive as it came from the factory.
This does not affect the operating system, which has its own counter.
To be honest, I have not done this in probably 3-4 years on a PC or other Linux, etc drive. I've only done it on an internal Macintosh notebook drive.
It probably did not need it as it was made before the short time Apple disabled reading a DVD as data. It was IMHO a "trial balloon" which failed.
Geoff.