So, I had a chance to get back to that calibration gizmo for my biochip front end amplifier (1 nA at the shot noise limit in a 100-MHz BW).
It turns out that it's possible to do a very nice job, assuming that the integration cap (C1 in the schematic) has zero inductance, but as much as 0.05 nH blows it out of the water. (Should have thought of that, of course, but oh well.)
Try running the sim at
With zero inductance in series with the cap, it switches in well under 1 ns. (The pHEMT diff pair switches in ~100 ps, and faster if I use more source current.) There's a certain amount of cruft in this schematic, e.g. I probably wouldn't bother with a current source to drive the sources of the pHEMTs, but you know how these things accumulate as you go along.
Any bright ideas?
Thanks
Phil Hobbs