Human Aging Now Biologically Reversible

length was significantly increased and senescent cells were reduced in a po pulation of healthy aging subjects. The study, part of a comprehensive rese arch program targeting aging as a reversible disease, is to be published in the peer-review journal Aging, and titled: Hyperbaric Oxygen Therapy Incre ases Telomere Length and Decreases Immunosenescence in Isolated Blood Cells : A Prospective Trial."

Huh, OK... I thought telomere length was something set in your genes... DNA . My limited understanding is that it's like the max_count(N) number in a f or loop. Copy this piece of genetic code N times, then no more. Evolution-wise it stops uncontrolled replication of one of your cells. (can cer) Hmm.. OK oxidative state may change 'extra' damage/ shortening.

Maybe the main benefit of exercise is keeping more oxygen in your blood? I'm going out to lift and carry more pieces of wood into my truck. :^)

George H.

Competing with 30 year olds on the dating circuit was tough enough, now have to compete with 70 y/os too!

The future is going to be a good time to be a 40 y/o single woman

e length was significantly increased and senescent cells were reduced in a population of healthy aging subjects. The study, part of a comprehensive re search program targeting aging as a reversible disease, is to be published in the peer-review journal Aging, and titled: Hyperbaric Oxygen Therapy Inc reases Telomere Length and Decreases Immunosenescence in Isolated Blood Cel ls: A Prospective Trial."

NA.

or loop.

ancer)

My understanding is there is an unknown chemistry of the telomere reading i ts substrate that controls everything replication related. The telomere mak ing mistakes, which increase in frequency with shortening, is how you end u p with all this age related cellular damage.

re length was significantly increased and senescent cells were reduced in a population of healthy aging subjects. The study, part of a comprehensive r esearch program targeting aging as a reversible disease, is to be published in the peer-review journal Aging, and titled: Hyperbaric Oxygen Therapy In creases Telomere Length and Decreases Immunosenescence in Isolated Blood Ce lls: A Prospective Trial."

DNA.

for loop.

(cancer)

?

They'll all be like Dolly- a new body with old genes.

ere length was significantly increased and senescent cells were reduced in a population of healthy aging subjects. The study, part of a comprehensive research program targeting aging as a reversible disease, is to be publishe d in the peer-review journal Aging, and titled: Hyperbaric Oxygen Therapy I ncreases Telomere Length and Decreases Immunosenescence in Isolated Blood C ells: A Prospective Trial."

DNA.

for loop.

(cancer)

its substrate that controls everything replication related. The telomere m aking mistakes, which increase in frequency with shortening, is how you end up with all this age related cellular damage.

Do you know the story about the (inadvertent) selection for long telomeres in US lab mice? (They only breed young males and females 'cause they had the most offspring .) search for "all of our mice are broken"

George H.

?

I cannot see how this can work. I'd wait to see if anybody can replicate the experiment a few times.

Telomere length is controlled by an enzyme, telomerase, which in mammals is turned off, which is the underlying cause of the count limit.

.

There was in 2010 an experiment in generically-engineered mice where telomerase was turned back on for a while. Aging was partly reversed

- gray hair went back to black, and so on.

. .

So, why is telomerase turned off at all? It appears to be one of the many evolved anti-cancer measures that all big complicated animals must have t o have a reasonable lifespan.

Joe Gwinn

You can increase the average length by replacing cells that have short telomeres with cells that have longer ones - by activating replication in residual populations that have longer ones. Pure speculation, but it's plausible.

CH

Is it a good thing if true? Kids challenge authority and push change. Old people: "We've always done it this way". Where would we be without Rock 'Em Sock 'Em Robots and Superball?

The elephant in the room problem is that if old people can hang around indefinitely, there must be a reduction in the introduction of new (young) people, or we run out of resources for species survival.

l."

This is Fred Bloggs. Even if he has got it right, and a few people are goin g to live a bit longer, it just going to be part of the recent improvement in life expectancy, which started around 1870 in advanced industrial countr ies, if not until in1925 in Africa, and still seems to be going on.

The consequence in advanced in most advanced industrial countries - the US may be industrial but it's not all that advanced - was that their birth rat es has dropped below replacement level, and population growth - if any - i s driven by immigration from less advanced countries.

We may run short on resources, but the species should survive - albeit perh aps with a winnowed gene pool.

--
Bill Sloman, Sydney

Also here