Hello Dimiter,
You have to make sure it's low enough. Ultrasound machines must provide noise immunity well past those 12 bits because of the TGC amps. Those amps provide an additional gain control of around 70dB, out of which
50-60dB are typically used. On most machines the range of frequencies to be processed would be 2MHz to 15MHz. The upper sideband for intracardiac echo machine can reach well above 40MHz.Having few lines crossing helps but issues can creep up when you connect the whole thing to the outside world. Now you have a dipole receiving antenna. When touching wires or connecting them to PE it can also become a loop antenna. One leg of the dipole is the DC power cable and other stuff on the DGND side, the other leg is the DUT connection on the AGND side. A common ground shorts out the center of that dipole for the most part. A split ground makes whatever sits across that split (typically ADCs) a receiver for whatever this unwanted antenna picks up.