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Agent does not keep any of its own settings in the Registry. The installer places un/install info, and if Agent is configured to be the default client for anything, that is set in the Registry, because that is a system setting.
Absolutely. If you're using a large enough portable drive device. I'd recommend either a USB thumb drive or portable hard drive, rather than a ZIP drive.
You can learn how to configure a different database location in the Help file. Help \\ Index \\ Directories and file types.
-- Jeffrey Kaplan Agent Support Team