I've been running WebPack 6.3 using wine under Gentoo linux for a while now with no problems. My wine version is 20041019. The only native .dll files I have in my windows directory are mfc42.dll and msvcp60.dll.
As I recall, I ran into no hitches during the install, it just worked normally. I may have had some pop-up windows appear under other windows, this is a common problem with wine and I'm used to it.
The GUI programs seem to work well although they are slow under wine. I tend to use the command line versions which seem to run at normal speed. I just run a unix script file to synthesize my project.
To call the individual programs (xst, map, etc) I created the following shell script and created symlinks to it for each program I wanted to use:
------------------------------------------------------------ #!/bin/bash export WINEPREFIX=/home/sag/wine/Xilinx export XILINX=c:\\Xilinx export WINEDEBUG=-fixme-all wine "$XILINX/bin/nt/${0##*/}" $*
------------------------------------------------------------
That last line in the script starts the xilinx program with the same name as the script. Since I use symlinks to this script I can use the same script for all the programs. For example, I have a symlink named xst which points to this script and it causes the windows native xst.exe program to be run under wine.
In general, it looks to me like the good Xilinx software engineers have intentionally made these tools wine friendly. I which everyone would do that (or even better support Linux natively).
Good luck,
Steve