Things I've seen, and even done, in Spice sims...
Bypassing voltage sources (not me!)
Worrying about resistor power dissipation
Using standard parts values, like 4.7K ohms or 33nF, when the control loop will be mostly code anyhow
Using +-12 or some such opamp supply voltages, and scaling signal levels to fit. The LT Spice universal opamps will work with hundreds, or thousands, of volt supplies.
Drawing hideously ugly schematics without a title, author, date, or named nodes.
So I'm rescaling a power supply sim (I'm waiting for a run to finish now) to have everything in actual 1:1 units. Then we will write the control loop code to work in those same real engineering units, not some goofy scaled integers or anything like that.
Keeping everything in true units as floats is ideal, but the RP2040 floating point ops are kinda slow, so we may express things as 32-bit values, 16 bits of signed integer and 16 bits of fraction, as a sort of fast and cheap float. But 12.5 volts is still visibly 12.5, just as if it were a float. That will be handy for debugging.
S16.16 is plenty good to express voltages and currents in a power supply.