Been through this exact build myself, so here's what I wish someone had told me up front. Don't daisy-chain power from panel to panel through those little 4-pin connectors. They'll work for a test pattern, but at full white the thin traces on the first panel end up carrying current for everything downstream, and you get dimming and heat where you don't want it.
Run the power supply output straight to each panel instead, or at least inject it every couple of panels. I used a small terminal block near the middle of the layout, with a fat pair of wires coming off the supply and shorter runs branching out to each panel from there. Anything from 18 gauge down works fine on the short branches, keep the main feed heavier. Keep data cables short and separate from the power runs where you can, or you'll chase ghosting for a week. One more thing on the supply side: screw everything down tight and give it a tug test before you power up. Those screw terminals on the cheap 5V bricks loosen up over time and a loose ground causes problems that look like data faults. Check the label on the back of your panels for max draw and add it up against what your supply can give you, then leave yourself some headroom.