I wouldn't go as far as calling it foolhardy, but it's a significant risk you don't want to take unless you really have to. And if you do, you'll have to do some risk management. As in: stock up on the part the moment you finalize that design decision.
That said, it may not be a particularly wise choice to design in *any* EPROM these days, unless you have very strict requirements mandating them. Flash or EEROM is just so much more easy to use during development --- and for final products, you can always use OTPs instead.