Sure, for that matter PCs are going away for the mainstream. In 10 years it will literally be like working on the Enterprise... the space ship Enterprise. Everyone will be using tablets and pads, there just won't be a need for the traditional PC except for specialties... like PCB layout, lol
There won't be any busses really. It will all be wireless. Maybe it will all be powered by a Tesla type power source too. lol
That doesn't change the fact that PCI was mainstream for well over a decade, more like 15 years!
BTW, are you capable of learning? Or have you reached your learning capacity?