Most of our boards have separate analog and digital ground planes. Worse, they're usually on the same layer - split! I've recently had some "wins" where I demonstrated that this was causing more problems than it was "curing" so have been consolidating planes (i.e. the other engineer is learning ;-) as I redesign boards.
Sometimes that's reality. That's why they make transformers and isolators. ;-)
Some want an inductor or ferrite in series with the analog power pins, but it scares me. At least one can put in 0-ohm resistors if they make things worse.