1.5 V
dissipation.
You should really understand when you can simplify a problem to a simple logic design and when to use more elaborate tools.
I have never seen a lossless transmission line.
There must certainly be something wrong, if you try to switch a million transistors at a time. Can you really fit this into a square or cube wavelength ?
In simplified transmission line theory, there is just the L/C ratio, however in the real world, you have to worry about the cable (skin) resistance R and dielectric conductance G.