Everybody's genome gets corrupted as it gets copied - not by all that much, but there are billions of cells involved. We known that since we've known that we had a genome.
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Re: We thought we had just one genome. It turns out we have trillions.
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We've known that cancer cells are cells with corrupted genomes since the 1960's. That's pretty specific.
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We've known about transposable elements for a while. Barbara McClintock's discovery of them in 1951 earned her a Nobel Prize in 1983.
There's no mechanism that could let the brain orchestrate their activity. You really are remarkably ill-informed.