In general?
In our entire universe!
This is worse than the effects of moving the cable around *after* an antenna match session.
10MHz is our std synching clock.Our simulators (stimulators) synch 1024 channels across 15 racks with mostly equal path lengths to within a picosecond of each other and we distribute reference signals across them all. Over coax. That way we know exactly when the data arrived or was sent with reference to the entire stimulus mosaic.