Not a problem at all. I never want to store WAV files anyway. Only thing is that then I'd have to delete them more frequently because I always hibernate my computers. Although it would take a very long time to overfill that RAM disk because sim runs always store to the same file name until you bump the rev level of your sim file. So one flush per week might suffice.
SSD is certainly on the top of my list for potential upgrades for this new PC once it gets here.