Hi, I have worked for two start-up electronics companies and two large multinationals as an electronic design engineer. In all cases it is best to follow the manufacturers guidelines with respect to calibration intervals. Although you may think they are using a short calibration interval as a money making exercise, you should stick to it. Their technicians are usually very helpful with questions like yours. When your customers come to 'visit' (audit) your facility before letting you supply them or design for them, they will want to ensure you are a quality company. Any auditor worth his salt will check your calibration schedule is in tune with the manufacturers recommendations, and if they find you making short-cuts here, they will go looking for short-cuts elsewhere, and if they find any, kiss bye-bye to that contract. It's a simple as that. In a start-up it's good to try new things, but not in this respect. I agree ISO is just 'do what you say you are doing'. In summary, start-ups shouldn't give customers any excuse not to do business with them.
Hope this helps!