I was trying to run RISC OS on a 3.5" TFT LCD display in 640x480 NTSC mode. Seems this issue is still live:
"Mouse pointer ? whilst a hardware mouse pointer protocol is being developed, the mouse pointer appears not quite to reach the edge of the screen and will leave a trail behind itself whilst dragging things around the desktop."
Probably less of an issue on a higher res display but makes the icons at the left and right of the screen unusable. Looks like I'm going back to Raspbian, unless there's an unofficial patch?