Bear in mind that the Micro-VGA is mainly designed to provide VGA capabilities to Micro controllers.
However the addition of USB input will allow not only PC's to interface to it, but also the new breed of ARM based micros with USB hosts on board.
And it has many advantages when used with a PC:
Unlimited number of additional screens, only restricted by USB specifications.
No internal PC hardware installation.
USB line length can be extended with off-the-shelf USB line extenders. Many types available.
The PC offers a quick test environment for the Micro-VGA, so that splash screens and menus can be tested before coding into your embedded application.
Consider this: You want a message board, or scoreboard with 2 lines by 8 characters, but you want it large.
How about a PC driving 16 by 15" LCD monitors, with one character per LCD, and all done with USB.
With LCD VGA monitors at around $200USD in quantities (dirt cheap if you use CRT's.), it will be a lot less than an LED matrix board. In fact, something perhaps in the order of $10K to $15K+ cheaper.
Future Expansion: Composite Video Out. RS-485, so that off-the-shelf USB to 485 converters can be used for line line driving for a mixture of short and long line drivers if required.