Not if, for example, the pin is declared as output in the symbol because leaving outputs unconnected is perfectly ok. Same for I/O or passive.
Operator error is one of the reasons why I will always hand-check netlists after finishing a circuit design. Bugs in CAD systems are the other.
Today's netlist went through sans error. Those color pencils really seem to be made only for kids. It says name, class and school on the box, in Chinese.